KMID : 1001920200630060738
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Journal of Korean Neurosurgical Society 2020 Volume.63 No. 6 p.738 ~ p.746
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Surgical Outcomes and Complications Following All Posterior Approach for Spinal Deformity Associated with Neurofibromatosis Type-1
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Park Byoung-Joo
Hyun Seung-Jae Wui Seong-Hyun Jung Jong-Myung Kim Ki-Jeong Jahng Tae-Ahn
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Abstract
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Objectives: The purpose of this study was to evaluate surgical outcomes and complications of spinal deformity associated with neurofibromatosis type-1 (NF-1).
Methods: From 2012 to 2018, patients suffering from spinal deformity associated with NF-1 who underwent surgical correction were identified. Demographic data and radiographic measures were retrospectively reviewed. Pre- and postoperative whole spine radiograph images were used to determine both coronal and sagittal Cobb angles. All of patients underwent 3-dimentional computed tomographic scan and magnetic resonance imaging scan to confirm dystrophic features. For evaluation of clinical outcomes, we surveyed the pre- and postoperative scoliosis research society-22r (SRS-22r) score.
Results: Seven patients with spinal deformity associated with NF-1 were enrolled in this study. The mean age of patients was 29.5¡¾1.2 years old. The mean follow-up period was 2.8¡¾1.4 years. The apex of the deformity was located in cervicothoracic (n=1), thoracic (n=4), and lumbar region (n=2). Most patients have poor bone quality and decreased bone mineral density with average T-score of -3.5¡¾1.0. All patients underwent surgical correction via posterior approach. The pre- and postoperative mean coronal and sagittal Cobb angle was 61.6¡¾22.6¡Æ and 34.6¡¾38.1¡Æ, 56.8¡¾18.5¡Æ and 40.2¡¾9.1¡Æ, respectively. Mean correction rate of coronal and sagittal angle was 44.7% and 23.1%. Ultimate follow-up SRS-22r score (average score, 3.9¡¾0.4) improved comparing to preoperative score (average score, 3.3¡¾0.9). Only one patient received revision surgery due to rod fracture. No serious complication occurred, such as neurological deficit, and viscerovascular injury.
Conclusion: The surgical correction of patients having spinal deformity associated with NF-1 is challenging, however the radiographic and clinical outcomes are satisfactory. The all posterior approach can be a safe and effective surgical option for patients having dystrophic curves associated with NF-1.
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KEYWORD
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Neurofibromatosis 1, Scoliosis, Kyphosis, Surgical procedures, Complication, Instrumentation
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